Home > Do spider vein removal pens work? > Do spider vein removal pens work? Do Spider Vein Removal Pens Work? Home > Do spider vein removal pens work? > Do spider vein removal pens work? Although Blue Light Pens are popular and widely marketed, there is no evidence they are effective in treating spider veins. Occasionally some people may report some minor difference in appearances after multiple treatment sessions, but they have limited role in effective management of spider veins.